Jilin scientific research team launches a more sensitive and convenient transgenic detection technology

News from Changchun, Jilin: The Jilin Academy of Agricultural Sciences and a research team from Jilin University have recently developed a highly sensitive genetically modified organism (GMO) detection technology that does not require preamplification of the target gene, which can improve detection sensitivity and convenience and is more suitable for onsite applications. According to the introduction, this achievement was completed through collaboration between the team of Li Feiwu from the Quality Standards Institute of the Jilin Academy of Agricultural Sciences and the team of Xu Shuping from the State Key Laboratory of Supramolecular Structure and Materials at Jilin University. The related paper has been published in the American Chemical Society journal ACS Measurement Science Au. Unlike traditional methods that first "copy" the target gene, the new technology instead amplifies the detection signal, combining methods such as catalytic hairpin assembly, CRISPR/Cas12a, and surfaceenhanced Raman scattering to identify the CaMV35S promoter sequence commonly found in GMO crops. The researchers said that this method has a lower dependence on complex instruments, is also compatible with portable Raman devices, and can provide outputs through colorimetric and fluorescent signals, offering support for scenarios such as agricultural production, food testing, and importexport inspection and quarantine.